Ativan is a well-known drug from the group of benzodiazepine derivatives, which are broadly used for the treatment of a large spectrum of psychological health issues from sleeping disorders to epileptic seizures. According to the directions to be used, Ativan additionally has a calming and enjoyable effect.
The drug is relevant for neurosis and anxiousness states accompanied by somatic issues, insomnia and panic assaults. It also has an anticonvulsant and muscle relaxant effect.
PHARMACODYNAMICS AND PHARMACOKINETICS
Pharmachologic impact of Lorazepam is due to its similarity with gamma-aminobutyric acid (GABA). Lorazepam belongs to the class of benzodiazepine derivatives and impacts the CNS buildings, liable for the regulation of emotional activity (these are limbic system and hypothalamus). The drug provides the flow of chlorine into the excited neuron, which in turn stabilizes neuron.
- sleeping drug
- muscle relaxant
Active substance is properly absorbed from the digestive tract, reaching its maximum concentration in the patient’s blood 2 hours later.
INDICATIONS AND CONTRAINDICATIONS
Ativan is widely used within the fashionable medicine for the treatment of such states and psychological diseases:
- various phobias
- psychosomatic disorders
- panic attacks
- obsessive-compulsive syndrome
- mental issues related to injuries
- behavioral disorders
- sleep disorders
- headache attributable to increased emotional stress and tension
- nervousness and anxiety
- consequences of the shock experienced
- sickness and vomiting, triggered by a course of chemotherapy
Also, Ativan can be utilized as a element of combination remedy during the therapy of continual alcohol habit. Sometimes, it is prescribed together with analgesic medicines to prepare the patients for operative or diagnostic interventions.
Ativan is utilized in drugs to remove the signs of psychological ailments:
- increased anxiety
- alcohol delirium
Ativan is a robust substance; therefore, it’s strictly forbidden to the patients, which have the following concomitant illnesses and conditions:
- hypersensitivity to the energetic substance or auxiliary components
- intolerance to different medication with an identical mechanism of action
- intoxication with substances miserable the central nervous system
- breathing problems
- liver failure
- apnea syndrome
- addiction to drugs, nicotine and alcohol (except withdrawal syndrome)
- alcohol intoxication
- acute renal failure
The use of Ativan is strictly forbidden to pregnant and breastfeeding ladies. If the use of Lorazepam is crucial for the mother’s well being, she should cease breastfeeding for the time of therapy with this medication. Also, this medicine is forbidden to the minor patients. Elderly sufferers must take Lorazepam with nice warning and intently monitor the body’s response to the drug.
The use of Ativan can affect the patient’s response price. Therefore, in the course of the therapy, you have to refrain from driving and managing different complicated mechanisms and restrict the work requiring caution.
According to the directions to be used, you want to start the therapy with Ativan with the bottom effective dose, and the course should not be long. With a large dosage and lengthy course, such substances could make the affected person addicted. In case of abrupt withdrawal of Ativan, chances are that the affected person may experience withdrawal or rebound syndrome; therefore, it’s necessary to cease the course by progressively decreasing the drug dose.